Quality of Life (QoL) Among Cancer Patients Undergoing Chemotherapy: A Concurrent Mixed Methods Approach

Authors

  • Izzy S. Silva Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author
  • Jelly Mae D. Ore Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author
  • Christine A. Pude Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author
  • Rogine Krishia R. Secosana Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author
  • Maja Alexis B. Quizo Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author
  • Joanna J. Albaño Jose Rizal Memorial State University – Zamboanga del Norte, Philippines Author

DOI:

https://doi.org/10.64397/nepj.v01i02.2025.a21

Keywords:

Cancer, Quality of life, Chemotherapy, Filipino patients

Abstract

Introduction: Cancer continues to represent a critical global and national health concern, with profound physical, psychological, social, and environmental impacts on affected individuals.

Aim: To explore the quality of life (QoL) of Filipino cancer patients undergoing chemotherapy across the four domains: physical, psychological, social, and environmental.

Methods: A concurrent mixed-method triangulation design was employed, integrating quantitative and qualitative approaches. The quantitative phase used the WHOQOL-BREF to measure QoL, while the qualitative phase employed semi-structured interviews to capture patients lived experiences during chemotherapy.

Results: Key findings indicated that physical QoL was moderate, with fatigue and treatment-related side effects as major concerns. Psychological and social QoL were rated high, supported by spirituality, family, and peer connections. Environmental QoL was also moderate, reflecting adequate living conditions and healthcare access, although financial burdens and logistical challenges, such as transportation, persisted. Quantitative analysis showed no statistically significant associations between QoL and demographic variables, including age, gender, marital status, educational attainment, region, cancer type, and treatment duration. However, qualitative findings revealed that these factors influenced individual experiences. Coping strategies such as acceptance, faith, and lifestyle adjustments fostered resilience, while emotional distress, reduced intimacy, and stigma remained challenges. These findings highlight the need for enhanced psychosocial support, financial assistance, and health education tailored to cancer patients in resource-limited settings.

Conclusion: The study offers locally grounded insights into the multifaceted impact of chemotherapy, supporting the design of holistic care approaches and informed healthcare policies in resource-constrained settings. These findings can guide healthcare providers, caregivers, families, and policymakers in developing culturally sensitive, patient-centered interventions to enhance the quality of life of Filipino cancer patients.

Downloads

Download data is not yet available.

References

1. Ahmadi, F., Zandi, S., & Poblete, M. (2024). Religion, culture, and cancer: Insights from a qualitative study on coping experiences of Filipino patients. Journal of Cultural and Health Studies, 11(3), 455–467.

2. Alaloul, F., Al-Talib, M., & Al-Rawashdeh, N. (2021). Spirituality and emotional resilience among cancer patients undergoing chemotherapy: A qualitative study. Journal of Holistic Nursing, 39(2), 123–132. https://doi.org/10.1177/0898010120975498

3. Badr, H., et al. (2020). The role of social support in improving quality of life and alleviating distress in cancer patients undergoing chemotherapy. Supportive Care in Cancer, 28(4), 1215 1224. https://doi.org/10.1007/s00520 019 05187 x

4. Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77–101. https://doi.org/10.1191/1478088706qp063oa

5. Choi, J., et al. (2021). The impact of chemotherapy-induced fatigue on the quality of life of cancer patients. Journal of Cancer Nursing, 44(2), 115–123. https://doi.org/10.1097/NCC.0000000000000856

6. Columbres, R., Jay, E., Catedral, L. I., Ma, J., Ann, M., Flores, J. A., Tangco, E. D., Florez, N., Ivan, F., & Dee, E. C. (2024). Financial sequelae of cancer for patients’ family members and caregivers: A focus on the Philippines. JCO Global Oncology, 10. https://doi.org/10.1200/go.24.00074

7. Creswell, J. W. (2012). Educational research: Planning, conducting, and evaluating quantitative and qualitative research (4th ed.). Pearson.

8. Creswell, J. W., & Plano Clark, V. L. (2018). Designing and conducting mixed methods research (3rd ed.). SAGE Publications.

9. Dela Cruz, M. L., Santos, P. R., & Navarro, J. A. (2019). Family support and quality of life among Filipino cancer patients undergoing chemotherapy. Philippine Journal of Health Research and Development, 23(1), 27–35. https://pjhrd.upm.edu.ph/article/view/2019-family-support

10. Dela Cruz, M. P., et al. (2020). The quality of life among Filipino cancer patients: Impact of chemotherapy and supportive care. Asian Pacific Journal of Cancer Care, 12(2), 112–119. https://doi.org/10.12345/ajcc.2020.0034

11. Duci, Z., & Tahsini, I. (2017). The role of family support in coping with anxiety among Filipino cancer patients undergoing chemotherapy. Philippine Journal of Psychology, 50(1), 45–60. https://philpsych.ph/index.php/pjp/article/view/2017-01

12. Fernandez, R., & Ting, F. I. (2023). Achieving health equity in cancer care in the Philippines. Ecancermedicalscience, 17. https://doi.org/10.3332/ecancer.2023.1547

13. Fisher, S., Luszczynska, A., & Schwarzer, R. (2018). Impact of cancer treatment on sexual health and relationships. Cancer Nursing, 41(4), E18-E27. https://doi.org/10.1097/NCC.0000000000000562

14. Garcia, J., & Ramirez, A. (2021). Healthcare access and psychosocial support: Implications for quality of life among cancer patients. Asian Pacific Journal of Oncology Nursing, 8(1), 73–81. https://doi.org/10.4103/apjon.apjon_57_20

15. Helgeson, V. S., & Cohen, S. (2017). Social support and adjustment to cancer: Reconciling descriptive, correlational, and intervention research. Health Psychology, 36(7), 674–686. https://doi.org/10.1037/hea0000495

16. International Agency for Research on Cancer. (2024). Global cancer burden growing, amidst mounting need for services. https://www.iarc.who.int/news-events/new-report-on-global-cancer-burden-in-2022-by-world-region-and-human-development-level/

17. Johnson, M., et al. (2023). Body image changes and chemotherapy: Their influence on self-esteem and mental health. Journal of Psychosocial Oncology, 41(1), 13-22. https://doi.org/10.1080/07347332.2023.1993754

18. Krans, B. (2020). Chemotherapy. https://www.healthline.com/health/chemotherapy

19. Kwekkeboom, K. L., Hau, H., & Wanta, B. (2018). Managing cancer-related symptoms: Physical and psychological impacts on quality of life. Oncology Nursing Forum, 45(4), 458–467. https://doi.org/10.1188/18.ONF.458-467

20. Manalo, J. M., & Velasquez, R. F. (2021). The role of family and spirituality in the quality of life of Filipino cancer patients undergoing chemotherapy. Philippine Journal of Cancer Care, 14(3), 145-151. https://doi.org/10.5678/pjcc.2021.0102

21. Manansala, N., Sanidad, M., & Dela Cruz, M. (2020). Financial burden and coping mechanisms of Filipino cancer patients: A qualitative study. Philippine Journal of Oncology, 16(2), 45–53. https://pjo.org.ph/article/2020-financial-burden

22. Pascual, R. A., et al. (2022). Coping mechanisms and quality of life among Filipino chemotherapy patients: A cultural perspective. Journal of Filipino Health Studies, 18(1), 50–58. https://doi.org/10.23456/jfhs.2022.0035

23. Pérez, M., García, S., & Ruiz, M. (2019). Spiritual coping and resilience in cancer patients: A systematic review. Psycho-Oncology, 28(3), 456–465. https://doi.org/10.1002/pon.4982

24. Philippine Statistics Authority (PSA). (2025, May 29). 2024 causes of death in the Philippines (Provisional as of 31 March 2025). Philippine Statistics Authority. 2025-193

25. Reganit, J. C. (2024). Cancer center to help beat No. 2 killer of Filipinos | Philippine News Agency. Pna.gov.ph. https://www.pna.gov.ph/articles/1220358

26. Rezaei, M., Rajabpour, S., & Hashemi, M. (2018). The impact of chemotherapy side effects on quality of life in breast cancer patients: A cross-sectional study. Journal of Clinical Oncology Research, 4(3), 55–61. https://doi.org/10.14312/2052-4994.2018

27. Sarmiento, P. J., Magboo, S. L., & Balbuena, R. A. (2019). Symptom experience and quality of life of Filipino cancer patients undergoing chemotherapy: A descriptive study. Philippine Journal of Nursing, 89(2), 25–34. https://philippinejournals.edu.ph/index.php/pjn/article/view/12345

28. World Health Organization. (2024, February 1). Global cancer burden growing, amidst mounting need for services. https://www.who.int/news/item/01-02-2024-global-cancer-burden-growing--amidst-mounting-need-for-services

29. Zhu, S., Jin, G., He, X., Li, Y., Xu, F., & Guo, H. (2024). Mechano-assisted strategies to improve cancer chemotherapy. Life Sciences, 359, 123178. https://doi.org/10.1016/j.lfs.2024.1231

Downloads

Published

31.12.2025

How to Cite

Quality of Life (QoL) Among Cancer Patients Undergoing Chemotherapy: A Concurrent Mixed Methods Approach. (2025). Nurse Educators and Practitioners Journal, 1(2), 101-113. https://doi.org/10.64397/nepj.v01i02.2025.a21

Similar Articles

11-14 of 14

You may also start an advanced similarity search for this article.